I'm currently experiencing the same thing too. The party stares dumbfounded at the doors in the tannery/cultist cave. Trying to put lockpicks in the quick item slot doesn't work. Double-clicking it does nothing. Unlike some of the other posters from above, I don't get any prompts about Mechanics.
I also tried to lock bash but haha, nope. All in all though, wow, what a promising experience. I haven't been able to get any games for a long time but this... so far it's been like coming home :3