I recently played a story mission with Kyra and Merisiel where Ghlorofaex was the villain (not sure which mission). After one of my fights against him, he moved into Kyra's hand. Now, he is permanently stuck in her deck. I can discard him for damage, but otherwise have a useless card clogging up my deck. Is there some way I can remove him? (I haven't been lucky enough to have him in my hand for a banish a card scenario yet.)

Villain/Henchman cards that sneak into your deck should be visible in the deck management screen if you press the "View All" button.

 

From there, just drag it out of the character's deck into the lower half of the screen and you should be able to press the triangle button to get rid of it and continue on with your game.

Thanks Ethics Gradient.  I'll keep that in mind for next time.  I had a harpy henchman end up in my four character run, but I took the opportunity in 6.1 to banish him when a haunt came a calling.  Now, I just need to find out why the villain keeps getting shuffled back into the deck in the last scenario before I can actually fight him.  Very Frustrating.