The start of every piece of verbal dialog with Calisca is missing. The first 4 or so words in any verbal dialog of hers (Starting area of the game and second area visited tested) will not be mentioned, she will immediatly start talking mid-sentance, sometimes you'll hear the sound of an end of a word when she starts talking. I could probably make a video of this, assuming Fraps doesn't cause the bug to not trigger. This affects ALL dialog with her as far as I can tell. Other NPC's seem to talk fine.
 
http://steamcommunity.com/sharedfiles/filedetails/?id=533997316 (First 6 words aren't heard)
http://steamcommunity.com/sharedfiles/filedetails/?id=533997372 (First 5 words aren't heard)
http://steamcommunity.com/sharedfiles/filedetails/?id=533997400 (Everything this guys says is audible/fine/correct)

This doesn't sound like the same issue as "Delay of Voice Overs, Music, and UI Windows" in the sticky topic, primarily because I am not virtualizing, emulating or playing the game over a network or anything like that. I am simply running it offline from my own PC. Single Player.

 

v2.02 (Game cache integrity verified)
Windows 10 x64
Intel i7 920 @ 2.66GHZ
ASUS P6T Motherboard
Gainward Geforce 560Ti 2GB with latest drivers
Integrated Audio
8GB DDR3 RAM

Hello Nicholas,

 

This bug sometimes happens if you get the springberries too fast while Calisca says "This is it". We have a bug entered in the system.

 

Thank you for your support. 

So, triggering the problem via the berries quest causes the audio issue with her for all future instances of her dialog until you save your progress and restart the game? Interesting.