I'm running it with a few problems on my old (built it around 2007/2008) pc.
Some specs:
AMD Athlon 64 X2 3800+ (Dual core, 2GHz)
2GB RAM
ATI Radeon HD 5450
I'm running at 1280x800, trying to keep FPS up. Occasional crashing as I transition areas which I'm thinking is memory related.
During some of the more "graphically intensive" moments (think when the biawac arrives at the end of the opening caravan section) I get some significant FPS drops.
And before you chime in, yes I know I need to upgrade but I simply can't afford it right now.
