An RPG in the Planescape or Darksun settings please. I loved Planescape Torment and I love the Planescape and Darksun settings. Obsidian are the only ones I'd trust to make a decent game in either setting. Furthermore, there haven't been any good D&D games for years, I think (hope?) there's an untapped fanbase there. I wouldn't invest in another fallout game. The Fallout setting has seen enough love recently, and I think Obsidian would add more to the RPG landscape by doing something different.