Ok so here's mine:
An RPG that has as its base a living, believable world that reacts to your actions and exists DESPITE you, not FOR you. A focus on realism. Like Darklands, but 20 years more advanced. Create good AI and game mechanics instead of scripted events. Non-linearity and a world you explore because its inviting, not because it's the only direction you can walk in. A grey world without clear good/evil choices or people, where everyone has a plausible motive for their actions.
Use that as the backdrop for intense, personal relationships and challenges with consequ