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Finally solved it: For anyone having trouble with the Steam install of AP, follow these directions: 1) Go to your Control Panel and Uninstall Programs. 2) Uninstall nVidia PhysX 3) Launch Alpha Protocol from within steam, and it should reinstall PhysX. This worked for me.

Neither works. If I launch directly from steam, it brings up the launcher. When I select "Play", I get a spinny Windows 7 circle-cursor for about 15 secs, then nothing. If I just click APGame.exe, I just get the spinny cursor for 15 seconds. I have tried running as administrator, running in XP service pack 2 compatibility mode, tried with almost all the compatibility checkboxes on or off in every conceivable arrangement. If you visit the SEGA boards, there are a number of threads at those forum that dead-end into SEGA support pages that no longer exist, also.

Yep, exactly the same here. Have done everything I've seen suggested in any forum. Please, Obsidian, how about some help here? core 2 duol 8400 @ 3.4Ghz 4Gb ram Radeon 5750 HD 1gb