I would like to see something in a similar vein to the classic BIS RPGs, in particular something where the original vision is as uncompromised as possible. The beauty of using Kickstarter is that commercial pressure won't be as great as usual and that's something I'd love to see Obsidian exploit to the full. Additionally, it would be wonderful to have a game which left something to the imagination (which 3D is particularly bad at and isometric particularly good at, IMO) and also has a setting (like PS:T, like Fallout) which takes us to an imaginary world quite different from the usual sub-Tolkien fantasy or cheesy Star Trek-esque sci-fi. Other than that, just let yourselves go crazy! )