Same happened to me pretty far into the game. Clock stopped at 14:35, lab door now locked. Started again, this time I can't collect gnat fuzz to craft gear. I tried Giving Up, reloading the save, reloading earlier saves that same day. Day before saves, the clock worked so I ended up redoing everything (which was a lot). What I did differently was place my respawn on top of the baseball, only thing I can think I might have done differently. This time I put my respawn on a rock, now I can't collect gnats. Not sure if that's enough to mess up the game this badly though. Not sure I have it in me to do this all over again. It's fun, but not THAT fun.