I have consistently had an issue where the game will crash on Tartarus. At this point it does not happen at any specific point in time, but happens most often in The Pit. If I manage to make it to the last elevator that takes the player to RAM the game crashes as soon as I activate the elevator controls. For context I am playing on an Xbox one X, but started my play through on a first gen Xbox One. Regardless of the system the game would always crash in The Pit. In my play through I have also managed to kill Sophie Akande before visiting Tartarus so the chairman is no longer in is normal spawn area.