Trying a single class Shattered Pillar Moonlike right now. So far the first island isn't so bad, but I don't think the faster power level growth helps out enough to offset the missing flexibility of a second class. Some fights were really hard, i.e. the three ethereal things that emerge from the puddle just before the adra pillar. Also I did not try the skeleton warriors at the dig site.
I think as soon as enemies will start to use more cc I am basically ****ed.
Just my experience from the first few hours of the game, might not hold up later on.