So I've done some searching on the forum and I see others complaining of this as well. Unfortunately, none of the solutions have worked for me.
This has been happening ever since I upgraded to Windows 10.
The game crashes at indeterminate intervals. I can play anywhere between 2 minutes to 45 minutes before it happens. It's completely unexpected, there's no specific action that seems to cause this behavior, but it has been happening since I upgraded from Windows 8.1 to 10.
Here's a link to a zip with a save game before it happened last, the output_l