Hi,
I got the same problem.
Basicaly the main quest "The man who waits" is broken.
I started the quest directly after the temple of woedeca and I began the quest and talked to the head of the sanitorium (Ethelmore) after that I talked to Audmer about the quest which resulted in the removal of the dialog option about the Assasin guild.
At that stage I stopped with the quest and started to continue with other quests after 14 hours of gameplay I continued with the quest "The man who waits". This resulted in Ethelmore acting like I already finished the Quest and when I ended the dialog the quest in the questlog didn't continue and Ethelmore is not talking to me anymore.
At any state when I go down to lvl 2 both doors are locked.
One workaround I found was to kill the 2 guards in lvl2 after that you get the Key for the main door, but the whole Sanitorium is hostile.
Here is the broken save with the ouput log files on googledrive: .
I tried to reproduce it by loading the 14 hours old save and doing some quests but I didn't find the issue that happened during the 14 hours play.
