I am also having this problem, it has shown up when I enter the Inn in Guilded Vale, and when I go upstairs in Brighthollow in our stronghold. This happens after the end of Act 2.
In both cases, it prevents me from being able to rest at either the Inn, or my own stronghold.
The loading screen progresses as normal, and then loads to a black screen, where I can hear music, sometimes ambient noise, and the mouse cursor. The HUD doesn't load, nor do any of the graphics.
I have tried loading earlier saves, to the point that I played back an hour or two to test whether it would still occur.