Game crashes very often

Hello

Description:
Pillars of Eternity crashes very often, but to irregular times. Sometimes it crashes five times a hour. Other times I can play three hours without any problems.
The crash can be freeze the game (more), kill/restart X-Server (less) or freeze the computer (less).


Steps to reproduce the issue:
unknown
 

Filelink:

https://www.dropbox.com/s/oc2i374lzhzakf5/PoE-Gamedata.zip?dl=0

System specs:

Computer Information:
    Manufacturer:  Unknown
    Model:  Unknown
    Form Factor: Desktop
    No Touch Input Detected
    
Processor Information:
    CPU Vendor:  AuthenticAMD
    CPU Brand:  AMD Athlon(tm) X4 880K Quad Core Processor     
    CPU Family:  0x15
    CPU Model:  0x38
    CPU Stepping:  0x1
    CPU Type:  0x0
    Speed:  4000 Mhz
    4 logical processors
    4 physical processors
    HyperThreading:  Unsupported
    FCMOV:  Supported
    SSE2:  Supported
    SSE3:  Supported
    SSSE3:  Supported
    SSE4a:  Supported
    SSE41:  Supported
    SSE42:  Supported
    AES:  Supported
    AVX:  Supported
    CMPXCHG16B:  Supported
    LAHF/SAHF:  Supported
    PrefetchW:  Unsupported
    
Network Information:
    Network Speed:  
    
Operating System Version:
    "openSUSE Leap 42.2" (64 bit)
    Kernel Name:  Linux
    Kernel Version:  4.4.73-18.17-default
    X Server Vendor:  The X.Org Foundation
    X Server Release:  11803000
    X Window Manager:  KWin
    Steam Runtime Version:  steam-runtime-beta-release_2016-12-05
    
Video Card:
    Driver:  NVIDIA Corporation GeForce GTX 550 Ti/PCIe/SSE2

    Driver Version:  4.5.0 NVIDIA 375.66
    OpenGL Version: 4.5
    Desktop Color Depth: 24 bits per pixel
    Monitor Refresh Rate: 60 Hz
    VendorID:  0x10de
    DeviceID:  0x1244
    Revision Not Detected
    Number of Monitors:  1
    Number of Video Cards Not Detected
    Primary Display Resolution:  1920 x 1080
    Desktop Resolution: 1920 x 1080
    Primary Display Size: 20,04" x 11,26"  (22,95" diag)
                                            50,9cm x 28,6cm  (58,3cm diag)
    Primary Bus: PCI Express 16x
    Primary VRAM: 1536 MB
    Supported MSAA Modes:  2x 4x 8x 16x
    
Sound card:
    Audio device: Realtek ALC662 rev1
    
Memory:
    RAM:  15985 Mb
    
Miscellaneous:
    UI Language:  English
    LANG:  de_DE.UTF-8
    Microphone:  Not set
    Steam Controller Cable and Base:  Not set
    Total Hard Disk Space Available:  463517 Mb
    Largest Free Hard Disk Block:  348126 Mb
    VR Headset: None detected