I've been searching online for some of the endgame weaponry, just the be sure I don't miss out. The Blade of Endless Paths has many components which can be found throughout the Endless Path of Od Nua (Dungeon below the Stronghold). Later, it can be forged into a powerful Estoc, a Two-Handed sword. 

My question is thus:
Is it possible to size with The Dozens in Defiance Bay (requirement to obtain Cloudpiercer, a powerful bow later on), but still make use of the NPC Dunstan (the Dwarf weapon-smith) inside the Knight of the Crucible's Keep in order to forge the Blade?

 

Spoilers? Not cool.