As primarily a solo player I would love to have an extra trinket pouch or mini inventory for trinkets.  So I can bring a selection with me to switch between as I'm exploring and they wouldn't take up so much space in the main inventory.  Also I think I would utilize them more rather than just picking a favorite and never really thinking much about them after that.  Also to be able to lock into place in the inventory the spaces I want my weapons, food, smoothies etc.  So I'm not searching around to see where things have rearranged themselves this time if I've switched out weapons with the hot bar or what have you.  A special row designated for "these items do not shift about the inventory"  would work fine for me too.

Yea, i see that in the same way.
Usually when walking around the garden you don't switch the smoothies every time you see a specific enemy.
For example, you would use the smoothe wich prevents toxic when encounter a wolf spider. But in the time you opened your inventory, find the specific smoothie in that chaos, put the correct smoothie in the "hotpick" menue - you are dead 😄

I do it like KJ9 and pick 1 smoothie i can easily craft and stick with that one.

I did so in Grounded 1 aswell. Except for Bosses - like the Wasp Queen - where you prepare your inventory ahead.

btw. why there are no "trash" smoothies like in grounded 1? where you could put anything in the mixer and just get a basic smoothie with no other benefit then quick healing?