So everytime I load in 2 of my mutations ha e been deactivated, also I may be being really blind but xbox series x appears to have e no quick switch mutation loadout option like Grounded had

Same thing is happening to me. I regularly have to re-check 2 of my 4 mutations. I don't know if it's specific to the order, but It's almost always the explorer and stamina mutations that get unchecked.

Same issue, even on my second game save that I'm working on. It's happening whether it's 3 or 4 mutations selected. Sometimes I load in and only one mutation is active. Xbox x console