Repro is launch PoE from Steam, and immediatly click another window (in my case Steam chat and Firefox). The effect is the mouse cursor is caged to the window you clicked instead of PoE. This is a normal usage case with multiple monitors. I have attached output_log.txt and os version. Neither upload works for me.
Operating System: Windows 8.1 Pro 64-bit (6.3, Build 9600) (9600.winblue_r8.150127-1500)
Can't EDIT: Put in spoiler tag because report is super long.