First of all. Avellone, I absolutely adore your Isometric RPGs (haven't played a lot of the newer games though. I own PS:T as a big box, DVD and on GOG.com.
However I do not think it will be possible to finance a big game through KickStarter (yet). For starters: A D&D license alone would consume most of what you could collect and the many millions of dollars needed for a full-length RPG is frankly overwhelming.
Seeing your responses to Mr, Gilbert and Mr. Schafer though I kindda got thinking... Ever thought of straying to other genres? I would love to see what kind of point-and-click adventure games you could dream up. Perhaps a Hyborian adventure? Or a Gabriel Knight'ish game based on the Cthulhu Mythos? (I believe both worlds have entered the public domain already?). Developing and adventure game would also make bug-testing somewhat easier, greatly reducing the cost...
On a somewhat unrelated note, I would love an RPG based on the GURPS system. Heard Fallout was supposed to use it, but it was for some reason decided against. Can't believe no-one has tried it since.