Came over from Steam forums to make sure word keeps spreading on this. Multiple users (and myself) on Win7, 8, and a few even on 10 are reporting that the game crashes to desktop when trying to load a save. This can even happen just trying to start a new game. I know you guys don't really check Steam forums but there are more reports over there than there are here at the moment. There is definitely a major bug since the game worked perfectly fine before the update and now is unable to work on a large variety of systems and configurations.
My own, if it helps.
Windows 7 Pro, 64 bit
GTX 980
i7-4790K
If you need any further info or have questions I'd be happy to answer as best I can. Thanks and have a good day.