Hi All,
I have hit the same bug where game was crashing on Xbox One X after killing slug queen. I have tried to avoid it many times under different scenarios and found a workaround:
1. Save the game FEW TIMES ON DIFFERENT SAVE SLOTS before entering the room with slug queen - this is required because some times the last save slot gets crashed as well.
2. If you have teammates with you, set "passive mode" for all of them - they should not attack any enemy.
3. Go to the room with the queen and speak to Ludovico. Once the queen ate him, go to one of small cabins with terminal - it does not matter right or left one. Shoot the queen before going into the cabin - queen should see and attack you. The main goal is to lure the slug queen into the cabin and kill it there without being attacked by her "babies" - it is quite easy.
Very important note - DO NOT kill any small slugs born by the queen!!! That is the reason to set "passive mode" for all your teammates before entering the room with the queen. One more important condition - "babies" should not see you when you are killing the queen. Otherwise they will attack you and entire workaround does not make sense.
4. Once slug queen is killed and you are not attacked by her "babies" save the game - game should not crash under this scenario.
5. Exit the game. Then load the last save slot created on previous step above. As you remember, you did not kill any slug "baby" before saving and leaving the game, but there should be no slug "babies" anymore after the game is loaded from the last save slot - this is the main indicator that you performed all steps above in a correct way!
DO NOT SAVE THE GAME UNTIL YOU RETURNED TO THE "UNRELIABLE" AND COMPLETED "Murder on Eridanos".
6. Then go to Ludovico's assistant and unlock the elevator to the outside (I did not attack the assistant).
7. Go outside and kill few infected security guards. Then run to the "UNRELIABLE" - DO NOT USE MAP TO TRAVEL THERE, JUST RUN.
8. Speak to Helen and Sedrick near the "UNRELIABLE", then enter it and speak to ADA - "Murder on Eridanos" will be completed then.
9. Fly wherever you want and save the game.
I hope this helps you to avoid hitting the bug.
