Heh I just ran into a problem on Onderon yesterday, checked the forums and didn't see much that would help me with this particular issue... I had an issue where after checking the droid, I went back and talked with Kiph then went and talked to Nikko. During the automatic transition sequence, loading the Merchant Quarter, the game would appear to hang when the bar hit about 80%. It actually had crashed, but since the app is written to be on top, you don't see the error windows unless you hit Control-Alt-Delete and pull up task manager. I lost only about 5 minutes of game play, thankfully, and next saved the game right before talking with Nikko. Still the same problem, reload again, same problem, tried one more time, same problem. Now unfortunately, not sure which of these fixed the issue since I did two things at once. I rebooted my computer (#1), loaded that save game, then exited the Cantina and re-entered. I saved (to a new file), then talked with Nikko and things worked well. Not sure exactly if this is what you are seeing, but maybe it will help.
Oh, BTW, I am running Vista 64bit Premium, with a Quad Core Intel CPU, 4GB RAM, and an NVIDIA GeForce 8600 GT adapter. It was hell getting the game to work, until going through the steps on this forum, thanks to all that have posted.