I only would if you are the type of player who doesn't really care about the shooting aspect and just want your companions to do all the work for you. I'm the opposite, where I would rather they don't do anything because even on hard difficulty, it was too easy with my companions killing everything too quickly. I liked to give them the science weapons so I could still use their effects but not have to limit my damage by using them myself. The 2 I had my companions use were the Gloop Gun and Mind Control Ray. Get one or more enemies floating through the air unable to do anything for the duration and then mind fork another to fight for me and basically gain an extra companion. Very useful versus the bigger enemies like the Mega Matiqueen's and really any Mega enemy since the Mind Control Ray actually affects them.