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Deadfire has a system of afflictions vs. inspirations. Any inspiration that is tied to a certain attribute will remove an affliction of that attribute

Here's a list of the inspirations/afflictions:
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So again: any inspiration of lets say MIG counters any affliction of MIG, any inspiration of PER counters any affliction of PER and so on. 

Theren there's also Resistences and Immunity to afflictions. Immunity is clear - Resistances reduce the "tier" of affliction by one (e.g. reduce Charmed to Confused). They can't be stacked.

Besides that you can use Resolve to shorten any hostile effect duration. Every point of Resolve over 10 means the hostile effect is 3% shorter. ALl attributes are capped at 35, so with RES at 35 you could shorten all negative effects on you by 75%.  

Then there are also items and consumables which do that. They stack with the effect from high RES.

There are also other effects (on items or abilites) which take away a fixed amount of seconds from hostile effects (see Clarity of Agony of Monks). Like for example -5 secs. Those also stack with the above.

And finally there are abilites that can suppress hostile effects. See stuff like "Suppress Affliction" of Priets for example. Paladins have something similar. Those don't shorten or remove negative effects but simply pause them. The effects will resume later (if the encounter's not ended by then).

So there are numerous ways to counter, shorten or suppress negative effects.

The biggest part is that inspiration vs. affliction mechanic I mentioned first. 

Then there's also spells that reflect other spells and so on, but that's a different story maybe. 

Edited by Boeroer

Deadfire Community Patch: Nexus Mods

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On 6/12/2020 at 3:47 PM, Boeroer said:

Deadfire has a system of afflictions vs. inspirations. Any inspiration that is tied to a certain attribute will remove an affliction of that attribute

Erh, this is PoE1 question 😛

Anyway,  for PoE1  a good  cleric spell of low level  for  halting negative spells is Suppress Affliction (2nd lvl). One to reduce the time of hostile effects is  Minor Intercession(priest 6th lvl too)   The first one has the benefit that is relatively common to find  rings which 2 uses of it per rest.
 

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