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Forgotten Sanctum Upper Bowel Obstruction


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The guide I'm using says

 

Enter the newly unlocked room and fight The Bowels Alchemist and a series of Dreambeasts. Afterward, loot Antiseptic Cream, then use it on the nearby pit to partially open the Passage to The Depths (do not take the passage yet or your main character will die).

At Excavation Site, steal the alchemical charge from the table, then place the charge on the nearby duct to blow it up, clearing the Passage.

Return to Temple of Revelation and speak to Drowsy Puke and request Deep Slumber, then go through the Passage.

I got the duct blown, which closed one of the three inputs. I got the cream but there's apparently an alchemy check that I can't pass; I think our collective score is around 12 and it's asking for 16. Any time I try to go down the hole, my main dies. What am I missing?

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