I'm sorry you have been experiencing this from the very beginning. I'm going to create a bug report for this and send it to the Programming team to investigate on your behalf. While they are looking into this there are a couple of things that we might need or suggest be done to make sure everything is up to snuff.
If the game is crashing and providing that error message, that means an entire folder with crash files should be generated and that has even more data that would be very helpful to the programmers. If needed, you can find instructions on how to find that folder here. The folder should be labeled with the date and time of the crash and have the ouput_log.txt, crash.dmp, and error.log inside. If the forum doesn't allow you to attach the files, feel free to send them to me at email@example.com along with your forum user name and a link to this thread as a reference.
Other things to help us would be to make sure your video driver for your Radeon RX 580 is updated with the latest driver and that your Windows 10 operating system is also up to date. Though these steps sound too simple to be true, they do tend to help many users with compatibility issues.
Thank you for trying these out, and sorry for the inconvenience this has casued.